BUY SDB-006 POWDER

BUY SDB-006 POWDER With an EC50 of 19 nM for human CB2 receptors and 134 nM for human CB1 receptors, SDB-006 is a medication that functions as a strong agonist for cannabinoid receptors. It was found after investigating the similar drug SDB-001, which was being sold illegally under the name “2NE1”. The metabolism of SDB-006 has been documented in the literature.

Manufacturers of synthetic cannabinoids frequently use isomerism to avoid detection and get around regulatory restrictions. Synthetic cannabinoids are the largest and most structurally diverse class of novel psychoactive drugs. The synthetic regioisomeric methoxy- and fluorine-substituted analogs of SDB-006 (N-benzyl-1-pentyl-1H indole-3 carbamate) were distinguishable by liquid chromatography-quadrupole time-of-flight mass spectrometry (LC-QTOF-MS) but not by gas chromatography-mass spectrometry (GC-MS).

Using a fluorescence-based plate reader membrane potential experiment, SDB?006 demonstrated strong cannabinoid receptor-agonistic effects at human CB1 EC50 values of 19 nM. In contrast to SDB-006, the potency of both methoxy- and fluorine-substituted analogs was lower; however, the 2 fluorinated analog (EC50 = 166 nM) was on par with the well-known synthetic cannabinoid RCS-4 (EC50 = 146 nM). SDB?006 and RCS?4 elicited a similar drop in body temperature (~0.7°C at a dose of 10 mg/kg) in rats using biotelemetry; this suggests that their potency was lower than that of the more recent synthetic cannabinoid AB?CHMINACA (>2°C, 3 mg/kg).

Technical Information
Formal Name: 1-pentyl-N-(phenylmethyl)-1H-indole-3-carboxamide
CAS Number: 695213-59-3
Molecular Formula: C21H24N2O
Formula Weight: 320.4
Purity: ?98%
Formulation: A crystalline solid
?max: 218, 291 nm
SMILES: CCCCCN1C=C(C(NCC2=CC=CC=C2)=O)C3=C1C=CC=C3
InChi CodeInChI=1S/C21H24N2O/c1-2-3-9-14-23-16-19(18-12-7-8-13-20(18)23)21(24)22-15-17-10-5-4-6-11-17/h4-8,10-13,16H,2-3,9,14-15H2,1H3,(H,22,24)
InChi Key: OLACYTSBFXCDOH-UHFFFAOYSA-N
Shipping & Storage Information
Storage: -20°C
Shipping: Room Temperature in continental US; may vary elsewhere
Stability: ? 2 years
WARNING This product is not for human or veterinary use.

See also
5F-CUMYL-PINACA
5F-SDB-006
APINACA
CUMYL-PICA
CUMYL-PINACA
CUMYL-THPINACA
SDB-001
SDB-005
STS-135

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