Buy AM-2201 crystal


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Buy AM-2201 crystal

Buy AM-2201 crystal. AM-2201, a recreational designer drug, functions as a powerful full agonist for the cannabinoid receptor that is nonselective, owing to its 3-(1-naphthoyl)-3-(5-fluoropentyl)indole structure. It is a member of the cannabinoid AM family that Northeastern University’s Alexandros Makriyannis identified.
A complete agonist for cannabinoid receptors is AM-2201. At CB1 and CB2, the affinities had a Ki of 1.0 nM and 2.6 nM, respectively. MAM-2201, a 4-methyl functional analog, most likely exhibits comparable affinities. AM-2201’s EC50 values for human CB1 and CB2 receptors are 38 and 58 nM, respectively. At dosages of 0.3¼3 mg/kg, AM-2201 causes bradycardia and hypothermia in rats, which is similar to the potency of JWH-018 in rats and suggests strong cannabinoid-like action.
Product Description

AM2201 (Item No. 10707) is an analytical reference material characterized as a synthetic cannabinoid.

AM2201 is regulated as a Schedule I compound in the United States.


New synthetic cannabinoids are starting to surface in global markets for recreational drugs. Toxicologists, physicians, and legislators who oversee public health must be informed about the pharmacological characteristics of these novel medications. 1H-indol-3-yl-1-(5-Fluoropentyl)1-naphthylAbused synthetic cannabinoid methanone (AM-2201) was first developed as a tool for researchers to study the endocannabinoid system.

Here, we assessed AM-2201’s pharmacodynamic effects in rats while also figuring out the drug’s and its metabolites’ plasma pharmacokinetics. Under pentobarbital anesthesia, male Sprague-Dawley rats were furnished with indwelling jugular catheters and surgically inserted temperature transponders.

under pentobarbital anesthesia, ally inserted temperature transponders and indwelling jugular catheters. After a week, rats were given subcutaneous injections of AM-2201 (0.1, 0.3, and 1.0 mg/kg) or its carrier, and catheters were used to take several blood samples. Just before each blood draw, core temperatures and catalepsy were recorded, and liquid chromatography-tandem mass spectrometry was used to analyze the plasma for drug and metabolites.

Two new types of synthetic cannabinoids, an AM-2201 benzimidazole analog (FUBIMINA, 1) and (4-methylpiperazin-1-yl)(1-pentyl-1H-indol-3-yl)methanone (MEPIRAPIM, 2), and three newly emerged phenethylamine derivatives, 25B-NBOMe (3), 2C-N-NBOMe (4), and a 25H-NBOMe 3,4,5-trimethoxybenzyl analog (5), were detected in illegal products distributed in Japan.

High-resolution MS, nuclear magnetic resonance analyses, and gas and liquid chromatography mass spectrometry (GC and LC MS) were the methods used for identification. Compounds 1 and 2 were entirely unique, in contrast to the archetypal synthetic cannabinoids, like JWH-018, which comprise a naphthoylindole moiety.

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Despite our best attempts to guarantee the correctness of the material in this datasheet, MyBioSource disclaims all liability for any errors or omissions. This datasheet may change at any time, without notice, at the sole discretion of Croweed.

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Technical Information
Formal Name: [1-(5-fluoropentyl)-1H-indol-3-yl]-1-naphthalenyl-methanone
CAS Number: 335161-24-5
Molecular Formula: C24H22FNO
Formula Weight: 359.4
Purity: ?98%
Formulation: A neat solid
?max: 218, 247, 315 nm
InChi Code: InChI=1S/C24H22FNO/c25-15-6-1-7-16-26-17-22(20-12-4-5-14-23(20)26)24(27)21-13-8-10-18-9-2-3-11-19(18)21/h2-5,8-14,17H,1,6-7,15-16H2

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Shipping & Storage Information
Storage: -20°C
Stability: ? 3 years

Where to Buy AM-2201 crystal


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