Buy ADB-FUBINACA Powder, Buy ADB-FUBINACA Powder For Sale
Buy ADB-FUBINACA Powder; In 2013, a designer medication called Buy ADB-FUBINACA Powder was found in synthetic cannabis mixtures in Japan. It was the third most prevalent synthetic cannabinoid found in substances that the Drug Enforcement Administration had confiscated in 2018.
A 2009 Pfizer patent describes the (S)-enantiomer of ADB-FUBINACA, which has been found to be a strong agonist of the CB1 and CB2 receptors with EC50 values of 1.2 nM and 3.5 nM, respectively. Like SDB-001 and STS-135, ADB-FUBINACA has a carboxamide group at the 3-indazole position. Given that ADB-FUBINACA varies from AB-FUBINACA solely in that a tert-butyl group has been added in place of the isopropyl group, it seems to be the result of rational drug design.
An analogue of ADB-FUBINACA, ADSB-FUB-187, containing a more functionalized carboxamide substituent was recently reported.
Technical Information
Formal Name: N-[1-(aminocarbonyl)-2,2-dimethylpropyl]-1-[(4-fluorophenyl)methyl]-1H-indazole-3-carboxamide
CAS Number: 1445583-51-6
Molecular Formula: C21H23FN4O2
Formula Weight: 382.4
Purity: ?98%
Formulation: A neat solid
SMILES: O=C(NC(C(N)=O)C(C)(C)C)C1=NN(CC2=CC=C(F)C=C2)C3=C1C=CC=C3
InChi CodeInChI=1S/C21H23FN4O2/c1-21(2,3)18(19(23)27)24-20(28)17-15-6-4-5-7-16(15)26(25-17)12-13-8-10-14(22)11-9-13/h4-11,18H,12H2,1-3H3,(H2,23,27)(H,24,28)
InChi Key: ZSSGCSINPVBLQD-UHFFFAOYSA-N
DEA Schedule: I
Shipping & Storage Information
Storage: -20°C
Shipping: Room Temperature in continental US; may vary elsewhere
Stability: ? 3 years
Legality
In the United States, ADB-FUBINACA is a Schedule I controlled substance.
Metabolism
Twenty-three ADB-FUBINACA major metabolites were identified in several incubations with cryopreserved human hepatocytes. Major metabolic pathways were alkyl and indazole hydroxylation, terminal amide hydrolysis, subsequent glucuronide conjugations, and dehydrogenation
Side effects
One case of coronary artery thrombosis mortality has been connected to intoxication with ADB-FUBINACA.
The use of this substance is believed to have contributed to at least 8 further deaths in Hungary in 2015; all of the victims were under 21.
WARNING This product is not for human or veterinary use.
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