Buy AM-2201 Powder

Buy AM-2201 Powder, AM-2201, a recreational designer drug, functions as a powerful full agonist for the cannabinoid receptor that is nonselective, owing to its 3-(1-naphthoyl)-3-(5-fluoropentyl)indole structure. It is a member of the cannabinoid AM family that Northeastern University’s Alexandros Makriyannis identified.

Cannabinoid receptors are fully agonistic by AM-2201 Powder. At CB1 and CB2, the affinities had a Ki of 1.0 nM and 2.6 nM, respectively. MAM-2201, a 4-methyl functional analog, most likely exhibits comparable affinities. AM-2201’s EC50 values for human CB1 and CB2 receptors are 38 and 58 nM, respectively. At dosages of 0.3¼3 mg/kg, AM-2201 causes bradycardia and hypothermia in rats, which is similar to the potency of JWH-018 in rats and suggests strong cannabinoid-like action.
Description of the Product

AM-2201 Powder (Item No. 10707) is an analytical reference material characterized as a synthetic cannabinoid.

AM2201 is regulated as a Schedule I compound in the United States.

Abstract

New synthetic cannabinoids are starting to surface in global markets for recreational drugs. Toxicologists, physicians, and legislators who oversee public health must be informed about the pharmacological characteristics of these novel medications. 1H-indol-3-yl-1-(5-Fluoropentyl)1-naphthylAbused synthetic cannabinoid methanone (AM-2201) was first developed as a tool for researchers to study the endocannabinoid system.

Here, we assessed AM-2201’s pharmacodynamic effects in rats while also figuring out the drug’s and its metabolites’ plasma pharmacokinetics. Under pentobarbital anesthesia, male Sprague-Dawley rats were furnished with indwelling jugular catheters and surgically inserted temperature transponders. A

fter a week, rats were given subcutaneous injections of AM-2201 (0.1, 0.3, and 1.0 mg/kg) or its carrier, and catheters were used to take several blood samples. Just before every blood draw, catalepsy and core temperatures were recorded.

Two new types of synthetic cannabinoids, an AM-2201 benzimidazole analog (FUBIMINA, 1) and (4-methylpiperazin-1-yl)(1-pentyl-1H-indol-3-yl)methanone (MEPIRAPIM, 2), and three newly emerged phenethylamine derivatives, 25B-NBOMe (3), 2C-N-NBOMe (4), and a 25H-NBOMe 3,4,5-trimethoxybenzyl analog (5), were detected in illegal products distributed in Japan.

The identification was based on liquid chromatography–mass spectrometry (LC–MS) and gas chromatography–mass spectrometry (GC–MS), high-resolution MS, and nuclear magnetic resonance analyses. Different from the representative synthetic cannabinoids, such as JWH-018, which have a naphthoylindole moiety, compounds 1 and 2 were completely new.

Precautions
The sole objective of all Croweed Products is scientific laboratory study; they are not intended for in vivo, preventive, therapeutic, or diagnostic uses. By making a purchase, you specifically guarantee and represent to Croweed that you will use and test any products you buy from them in a way that complies with industry standards.

Orders where we reasonably suspect the intended usage will not comply with our acceptable guidelines will not be processed by Croweed or its authorized distributors.
Notice of Disclaimer
Despite our best attempts to guarantee the correctness of the material in this datasheet, MyBioSource disclaims all liability for any errors or omissions. This datasheet may change at any time, without notice, at the sole discretion of Croweed.

It is the responsibility of the customer to report product performance issues to Croweed within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Technical Information
Formal Name: [1-(5-fluoropentyl)-1H-indol-3-yl]-1-naphthalenyl-methanone
CAS Number: 335161-24-5
Molecular Formula: C24H22FNO
Formula Weight: 359.4
Purity: ?98%
Formulation: A neat solid
?max: 218, 247, 315 nm
SMILES: O=C(C1=CC=CC2=C1C=CC=C2)C3=CN(CCCCCF)C4=CC=CC=C43
InChi Code: InChI=1S/C24H22FNO/c25-15-6-1-7-16-26-17-22(20-12-4-5-14-23(20)26)24(27)21-13-8-10-18-9-2-3-11-19(18)21/h2-5,8-14,17H,1,6-7,15-16H2

See also
AM-694
AM-1235
AM-2232
AM-2233
JWH-018
SDB-005
THJ-018
THJ-2201
MEPIRAPIM
NM-2201

Shipping & Storage Information
Storage: -20°C
Stability: ? 3 years

Where to Buy AM-2201 Powder